Students of XXXIX

Martina Bertocchi

Study of Congenital Central Hypoventilation Syndrome, in particular the role of PHOX 2 B in differentiation of patient derived iPSC neurons

Roberta Ciceri

Characterization of the     role and mechanisms  of endothelial dysfunction in patients with antiphospholypid syndrome.

Riccardo Esposito

Cell metabolism modulation for the development of a new therapeutical approach in regenerative medicine field for the nervous tissue

Sabrina Invernizzi

Study of pathomechanisms related to TARDBP gene in amyotrophic lateral sclerosis (ALS) using patient-derived iPSC models.

Laura Lociuro

The beneficial effects of persistent Sirtuin1 activation in dystrophic muscles and at exploring the synergic effects of the combination between micro-dystrophin gene therapy and Sirtuin1 activation.

  Arteda Paplekaj

The characterization and the preclinical validation of a novel epigenetic target in the treatment of Post-Traumatic Stress Disorder.

Rebecca Polidori

The application of artificial intelligence tools for the analysis of tumor tissues to study the cellular composition and the spatial organization of the tumor microenvironment.

Letizia Russo

The investigation of a novel role for MeCP2 in the regulation of brain aging in Rett Syndrome mice model.

Elena Vecchi

Understanding the physiological role of Haus7 in neuronal maturation and its potential role as modifier gene of Rett syndrome.

  Valentina Traini

The role of the recently identified organelle named paraspeckle and its protein components in Multiple  Myeloma pathogenesis

Isabella Zafferri

3 D culture system of human organoids, in particular, mini guts from patient exosomes to personalize therapy in  Crohn’s disease

Students of XXXVIII

Simone Balin

Immunopathogenesis of thymic epithelial tumors and related autoimmune diseases

Anna Beneggi

Characterization of the molecular circuits that define the function of regulatory CD4 T lymphocytes

Francesca Cadelano

Priming strategies to enhance the effect of the secretome of mesenchymal stem/stromal cells in counteracting osteoarthritis through the action of EVs

Sabrina D’Amelio

Role of oxidative stress in vulnerability to psychiatric diseases and in the mechanism of action of psychotropic drugs

Ilaria Gentile

The zebrafish model as a means to validate the role of new pathogenic mechanisms and potential treatments for high-impact congenital diseases

    Angela    La Grua

Correction of the genetic defect in induced pluripotent stem cell lines through chromosome transplantation

Paolo Marzano

Study of the escape mechanisms of metastatic colorectal cancer from immunological surveillance.

Francesca Minnai

Integrating pharmacogenomic and pharmacometabolomic data for personalized opioid therapy for advanced cancer pain

Emma Nozza

Molecular mechanisms regulating the Insulin-like Growth Factor (IGF) system in adrenal carcinomas

Giulia Pruonto

Study of the effect of Tumor Educated Macrophages on neural cells (Ex DM 352/2022)

Jawdat Sandakly

Identification and characterization of new modifier genes of Rett syndrome

Alessia Troilo

New regulatory mechanisms of macrophage function: the role of MS4A proteins

Students of XXXVII

Alessandro Frigo
Alessia Amenta
Carolina Dossena
Elena  Romito
Martina Breccia
Sabrina Briguglio
Silvia Rosanna Casati
Emanuela Esposito
Giorgia Fedele
Maria Balbontin
Luana Binaschi

Students of XXXVI

Roberta Bordo

Single-cell CRISPR pooled screening to dissect gene–function relations in colo-rectal cancer derived organoids.

Alessia Marica Brix

Zebrafish (danio rerio) as a model system for the functional validation of candidate genes in human diseases.

Valeria Casiraghi

Aggregation mechanisms of TDP-43 protein in response to stress in amyotrophic lateral sclerosis and therapeutic approaches

Valentina Cazzetta

Innate immunity and tumour escape mechanisms in the prognosis and therapy of ovarian and uterine cancers

Ana Cuadros Gamboa

Use of induced pluripotent stem cells iPS for the study of Autonomic Nervous System (ANS) disease: focus on Congenital Central Hypoventilation Syndrome.

Giuseppina De Rocco

Stimulating neuronal activity in Mecp2 deficient brain to improve typical symptoms of Rett syndrome

Sara Franzese

Role of innate immunity in the pathogenesis of primary biliary cholangitis

Zulkifal Malik

Combined pharmacological approaches for spinal cord injury regeneration

Alessandro Manzo

Development of novel therapeutic approaches to aggressive thyroid cancers, in vivo and in vitro studies

Students of XXXV

Assunta Cancellara

Role of endothelial dysfunction in the pathogenesis of unprovoked venous thromboembolism

Vanessa Favasuli

Dissecting the pathogenetic role of deregulated non-coding transcripts associated with DIS3 gene mutations in Multiple Myeloma

Viola Ghiandai

Multicellular spheroids: a new model for thyroid cancer studies and drug screening. 

Stefano Gianoli

Novel macrophage tetraspan molecules: biological relevance immune responses and therapeutic exploitation

Alessandra Maielli

The interplay between cellular aging and immune response in human colorectal liver metastasis: senescence as a new prognostic marker?

Federica Miramondi

Neural stem precursor cell therapy: a novel therapeutic approach for the treatment of Rett syndrome

Serena Santangelo

Investigation of pathomechanisms associated to amyotrophic lateral sclerosis in patient-derived cells

Clementina Sitzia

Obesity and cardiovascular disease: the role of the receptor for advanced glycation end products (RAGE) in heart steatosis

Vittoria Spero

Molecular mechanisms underlying the association between psychiatric disorders and inflammation as potential pharmacological targets

Students of XXXIV

Ramona Bason

Epigenetic characterization of tumor infiltrating CD4+ regulatory T cells

Michela Calvi

Pattern of innate immunity response in patients affected by myelodysplastic syndrome (MDS) either before and after hematopoietic stem cell transplant (HSCT)

Clara Maria Cambia

Involvement of ATM and ATR in the regulation of the central nervous system development

Sara Casati

In vitro cross-talk between osteosarcoma (OS) cells and mesenchymal stem/stromal cells (MSC): lipidomic analysis of Evs derived from both MSC- and OS- cells

Maria Nicol Colombo

Unravel the mechanisms tuning neuronal network electrical properties in ALS

Domenica  Giannandrea

Extracellular vesicles-mediated communication in remodeling multiple myeloma microenvironment: a new role for the Notch pathway

Sara Mazzoleni

Solving the puzzle of protocadherin-19 mosaicism to understand the pathophysiology of PCDH19 Female Epilepsy (PCDH19-FE)

Alex Pezzotta

Zebrafish as a model to study common molecular mechanisms involved in cancer and neurodegenerative diseases

Davide Saronni

Zebrafish: an innovative model for neuroendocrine tumors.

Roberta Scrimieri

Endothelium in Petri dish (2D) or on a chip (3D): studies on endothelial function/dysfunction

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